Sad to hear of the passing of Ursula K. Le Guin, a trailblazer for female authors in the realms of science fiction.
As you may know, I'm a huge Ghibli fan, and there's a scene from the Ghibli version of Tales from Earthsea that came to mind on hearing the news:
No man nor any living thing in this world preserves their life forever. But only to men is it given to know that we must die, and that is a precious gift. This life that is both our torment and our treasure was never meant to endure for eternity. Life is a wave on the sea. Would you force the sea to grow still to save one wave? To save yourself?
Always loved those last couple of lines, but now they seem rather more of a lamentation.